Certified Registered Nurse Infusion Exam Prep
Free practice questions

Free CRNI Practice Questions

10 exam-style questions with answers and explanations, straight from our 1,035-question bank. Tap an answer to check yourself. When you're ready, take the scored version in the free practice test.

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The CRNI exam has 140 questions and runs 2 hours 30 minutes.

These 10 free CRNI questions are organized by exam domain, so you can see how each part of the Certified Registered Nurse Infusion blueprint is tested. Reveal the answer and explanation under each question.

Domain 1: Principles of Practice 29% of exam

Question 1

A nurse is preparing to remove a non-tunneled central venous catheter from an adult. Which action best reduces the risk of air embolism during removal?

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Correct answer: C - Place the patient supine or in Trendelenburg and have them bear down (Valsalva) on withdrawal

Question 2

A nurse reviews the chain of infection. The pathogen has left its reservoir and is being transmitted on contaminated hands. Which link must be broken to interrupt spread at THIS point?

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Correct answer: B - The mode of transmission

Question 3

Before accessing a needleless connector on a central line, the nurse should perform which action to reduce intraluminal contamination?

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Correct answer: D - Scrub the connector using friction with an appropriate antiseptic, then let it dry

Domain 2: Access Devices 33% of exam

Question 4

A home infusion patient needs 4 weeks of IV therapy with a solution measured at 1,100 mOsm/L. Which vascular access device is most appropriate?

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Correct answer: A - A central vascular access device such as a PICC

Question 5

A patient's central catheter flushes sluggishly and blood cannot be aspirated. The occlusion is confirmed as thrombotic. Which intervention is consistent with current standards?

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Correct answer: D - Instill alteplase 2 mg, allow it to dwell, and then reassess catheter function

Question 6

Which statement about a midline catheter is accurate and should guide therapy selection?

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Correct answer: A - It ends in a peripheral vein and is not for continuous vesicants or parenteral nutrition

Question 7

A 3-in-1 (total nutrient admixture) parenteral nutrition solution containing lipids is being administered. Which in-line filter is appropriate?

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Correct answer: C - A 1.2-micron filter that accommodates lipid particles

Domain 3: Infusion Therapies 38% of exam

Question 8

Thirty minutes into a transfusion of packed red blood cells, a patient develops fever, chills, flank pain, and red-tinged urine. What is the nurse's FIRST action?

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Correct answer: B - Stop the transfusion and keep the line open with 0.9% sodium chloride

Question 9

Two hours after starting a unit of blood, an elderly patient with heart failure becomes dyspneic and hypertensive with distended neck veins; BNP is elevated and symptoms ease after a diuretic. Which reaction is most likely?

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Correct answer: D - Transfusion-associated circulatory overload (TACO)

Question 10

An adult with serum potassium of 2.9 mEq/L has an order for IV potassium replacement through a peripheral line. Which parameter reflects safe administration?

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Correct answer: A - Infuse at a maximum of 10 mEq per hour using an electronic infusion pump

That's 10 of 1,035

The full bank has 1,025 more CRNI questions with explanations.

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